Description
The MiniBeadbeater-96 disrupts cells and tissue by violently shaking a sample inside a classic 2 ml microvial or standard deep well microplate partially filled with tiny ceramic or steel beads. Complete cell disruption is achieved in 2 to 3 minutes of bead-beating. A common application is nucleic acid extraction. Up to 400 mg of tissue is added to a vial containing glass or ceramic beads and a nucleic acid extraction solution. The synergy of combining mechanical cell disruption and nucleic acid extraction simultaneously gives very high yields of high quality RNA or DNA. Protocols developed earlier using smaller capacity models of the MBB are transferable with little if any modification.
The Mini-Beadbeater-96 is high-energy, high-throughput cell disrupter. In a single 1-3 minute batch run it handles up to 192 samples using a deep-well microplate format or 45 samples in 1.5 or 2 ml screw-cap microvials. In a busy day thousands of samples can be processed.
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